Limited edition
WRINKLE SHOT DEBUT KIT
A limited-edition kit that allows WRINKLE SHOT to be tried as a set. It improves wrinkles*1 and creates skin with a feeling of firmness and elasticity. Designed for first-time users of WRINKLE SHOT.
WRINKLE SHOT SERUM N [Quasi-drug] 10 g
WRINKLE SHOT GEO SERUM PROTEAN [Quasi-drug] 9 g
*1: Due to WRINKLE SHOT SERUM N
¥7,920 (incl. tax)

WRINKLE SHOT GEO SERUM PROTEAN
[Quasi-drug] (Serum)
A new protein concept for your skin.
A serum containing protein* that supports rich expression* and aims for robust, full* skin.
40 g ¥11,000 (incl. tax)
Refill 40 g ¥10,450 (incl. tax)
Allergy tested (formulated to minimize the risk of allergy)

WRINKLE SHOT SERUM N
[Quasi-drug] (Serum)
Introducing the renewal of WRINKLE SHOT, Japan’s first ever medicated wrinkle improvement* cosmetic.
20g ¥14,850 (incl. tax)
Lasts For: Approx. 4 months for 1 site; Approx. 2 months for 2 sites.
Allergy tested (formulated to minimize the risk of allergy)

*Wrinkle improvement: Recognized as achieving a significant change in wrinkle improvement in the Wrinkle Grade evaluation standard listed in the
Japanese Cosmetic Science Society’s “Guidelines for Evaluation of Anti-Wrinkle Products” for the approval of new functions.
*Supports rich expression: Refers to elasticity of the stratum corneum
*Full: Due to moisture
*Protein: Refers to “Hydrolyzed Royal Jelly Protein,” a component of the moisturizing complex S Protein Liquid
Details
Details
A Dynamism Delivery Formulation containing oils with ductility, allowing the formula to spread dynamically on the skin
Uses small-sized, low-viscosity oils that spread to every corner of the skin.
As NEI-L1 has excellent affinity with water, we have developed an original formulation that stays stable when adding water and water-soluble components.
For this renewal, we have succeeded in adding three new ingredients. The water-soluble/oil-insoluble characteristics of NEI-L1 have been used to create a formula with other compatible ingredients.

“NEI-L1” is a quasi-drug active ingredient unique to POLA, found out of approximately 5,400 types of ingredients.
“NEI-L1” is a quasi-drug active ingredient that inhibits neutrophil elastase.
NEI-L1 is a component created from four amino acid derivatives that suppresses the activity of neutrophil elastase for wrinkle improvement.
It corrects the balance of dermis component generation and degradation for wrinkle improvement.
